Stem Cell Advances in Pneumonia Treatment. Over the past two years, there have been significant advancements in studying how to treat patients with pneumonia, primarily focusing on mitigating the effects caused by COVID-19. Recent studies have highlighted critical progress in pneumonia treatment and other respiratory conditions, offering new insights and hope.

Groundbreaking Research at the University of Granada

Firstly, The University of Granada, in collaboration with the Virgen de las Nieves Hospital in Spain, conducted research using experimental models. They discovered that mesenchymal stem cells are activated through radiation. This could be pivotal in treating septic shock and pneumonia induced by the coronavirus.

Innovative Clinical Trials in Jakarta Hospitals

Simultaneously In Jakarta, Indonesia, four hospitals undertook a clinical trial. The first of its kind targeting intubated and severely ill COVID-19 pneumonia patients. This trial utilized an unmodified, naive form of stem cells. Out of the 40 adult patients in intensive care who participated in this double-blind, controlled, and randomized study. Half received intravenous infusions of umbilical cord-derived mesenchymal stromal cells. Remarkably, “The survival rate of those who received stem cells was 2.5 times higher and increased further (4.5 times) in COVID-19 patients with other chronic conditions,” according to Ismail Hadisoebroto Dilogo, one of the research leaders.

Pioneering Projects in Spain

Secondly, Specialists in Infectious Diseases at the Virgen del Rocío University Hospital in Spain have launched a project administering stem cells from adipose tissue to evaluate their anti-inflammatory effects against COVID-19-induced pneumonia.

Insights from the University of California, San Francisco

however, a study at the University of California in San Francisco. Uncovered a unique trajectory of stem cells in lungs damaged by COVID-19 and pulmonary fibrosis, revealing how diseases trigger abnormal stem cell repairs that alter lung architecture. This research, published in ‘Nature Cell Biology’, used stem cell organoid models to explore new paths for treatment.

Multicenter Study Led by the University of Navarra Clinic

Finally, A multicenter study led by the University of Navarra Clinic, along with other notable Spanish hospitals, demonstrated that cell therapy using adipose tissue-derived stem cells improves the prognosis of critically ill patients. This study, published in EClinicalMedicine, part of The Lancet group, marks a significant step forward in stem cell therapy.

Conclusion

In conclusion, Multiple ongoing studies explore stem cell applications in pneumonia treatment utilizing various stem cell sources like bone marrow, fat, and the placenta. These studies are crucial in demonstrating the benefits of stem cell use in medical treatments.

For more in-depth knowledge, we invite you to read our article on What Are Stem Cells?

Stem Cell Advances in Pneumonia Treatment