The treatment of diabetic feet with adult stem cells is obtaining outstanding results in several studies worldwide.
The American Diabetes Association estimates that complications of UPD cause 85 percent of one leg amputated every 30 to two worldwide.
But today, doctors can save lower limbs from amputation. Stem cells have the ability to replace damaged tissue with new tissue, resulting in the closure of ulcers.
In the case of arterial insufficiency, stem cells produce vascular neogenesis. This process allows for the formation of new arterial vessels. These new vessels can carry oxygen to the areas of ischemia. As a result, wound healing is achieved in a convincing way.
Doctors obtain adult stem cells from periumbilical fat tissue for treating diabetic feet with stem cells. The results are wonderful, patients heal their wounds, decrease the discomfort of their neuropathy and decrease the levels of glycemia in the body, thus reducing the doses of hypoglycemic agents.
In summary, the treatment of diabetic feet with adult stem cells is a safe alternative treatment that will improve the quality of life, avoiding complications and amputations in patients.
Phase 1 clinical trial published in ‘STEM CELLS Translational Medicine’.
The researchers injected 63 candidates for amputation, aged 35 to 70 years with type 2 diabetes and chronic UPD, in the trials of the study published in the journal Stem Cells Translational Medicine. Additionally, the injection was a preparation containing adult stem cells extracted from their own fat. This innovative treatment approach aimed to restore damaged blood vessels and promote blood circulation, ultimately facilitating healing.
Doctors injected stem cell therapy directly into the ulcerated foot. They hoped to restore damaged blood vessels, promote blood circulation, and facilitate healing.
The researchers assessed ulcer closure at six months. In total, 51 patients achieved 100 percent UPD closure. Additionally, eight patients had greater than 75 percent closure.
Only three required early amputations and one patient died. The treatment induced regeneration of the blood vessels surrounding diabetic foot ulcers, accelerating healing and without serious side effects.
“this work should be reviewed as it demonstrates the possibility of a novel cell injection therapy that can alleviate pain and infection, accelerate wound healing and possibly prevent amputation.”
Anthony Atala. Director of the Wake Forest Institute for Regenerative Medicine.
American Diabetes Association
The American Diabetes Association estimates that the world experiences an amputation of a leg every 30 seconds, with diabetic foot ulcer complications causing 85% of these amputations.
To date, there is no effective form of treatment for this condition. However, these results could help many people around the world to avoid amputations. “The authors of the study concluded that stem cells can safely treat chronic UPD,” stated the study. They also noted evidence of efficacy in wound healing and mechanisms of action including vascular repair and/or angiogenesis.
If you wish to learn more, please visit our article Stem Cells for Diabetes.
Approximately 15% of people with diabetes must have a foot or leg amputated. In addition, according to estimates by the American Diabetes Association, globally, a leg is amputated every 30 seconds, 85% of which is caused by diabetic foot ulcer complications.
To date, there is no effective form of treatment for this condition and these results could help many people around the world to avoid amputations. “The authors of the study concluded that stem cells can safely treat chronic UPD and showed evidence of efficacy in wound healing. They also identified mechanisms of action, including vascular repair and/or angiogenesis,” stated the study.
If you wish to learn more, please visit our article Stem Cells for Diabetes.
